Managing Expectations: Who Should and Shouldn’t Use GLP-1 Therapies?

GLP-1 receptor agonists, including semaglutide (containing the same active ingredients as Ozempic^® and Wegovy^®) and tirzepatide (with the same active ingredients as Mounjaro^® and Zepbound^®), have gained attention for their role in blood sugar control and weight management, particularly in individuals with obesity. While these medications are highly effective, they are not suitable for everyone. Determining if someone is a candidate for GLP-1 medication depends on individual health history, medical guidelines, and a personalized approach. Affinity Urgent Care, serving Alvin, La Marque, and Galveston, Texas, is here to explain who should use GLP-1 therapies.

Is GLP-1 Right for You?

The first step when considering GLP-1 therapy is consulting a health care provider. These medications can be an excellent choice for individuals with obesity, but they have specific eligibility criteria and potential risks. It’s essential to understand how GLP-1 therapies fit into a comprehensive health care plan so you can make an informed decision.  

Guidelines for Body Mass Index (BMI) and Blood Glucose

GLP-1 therapies mimic the GLP-1 hormone, which controls appetite and blood sugar levels. Health care providers typically consider GLP-1 receptor agonists for individuals with the following conditions who meet specific criteria:

Weight Management & Obesity

Semaglutide and tirzepatide are FDA-approved for weight loss with the following BMI guidelines:

• Have a BMI of 30 or higher (obesity)

• Have a BMI of 27+ with weight-related conditions (diabetes or hypertension)

These medications support weight loss, which may indirectly improve blood glucose levels in individuals with excess weight. Some GLP-1 drugs also reduce heart disease risks and are beneficial for people who have high cardiovascular risk factors.

Conditions That Might Conflict With GLP-1 Use

Certain medical conditions may conflict with GLP-1 therapies, making it essential to consult a health care provider. Some contraindications include:

• Gastrointestinal disorders, such as gastroparesis, which can worsen with GLP-1 use
• Pancreatitis, as GLP-1 medications may increase the risk of episodes
• Severe kidney disease, which can impair medication clearance
• History of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN2)

In addition, GLP-1 therapies are not recommended during pregnancy, so those who are pregnant or planning to conceive should consider alternative treatments.

The Importance of a Personalized Treatment Plan

GLP-1 receptor agonists are most effective when incorporated into an individualized health care plan. A personalized treatment plan should include the following:

• Medical supervision and regular checkups to monitor progress, adjust dosages, and address side effects

• Lifestyle modifications like proper sleep, stress management, and meal timing

• Nutritional guidance to enhance weight loss

• Physical activity to maximize the benefits of GLP-1 medications

Discussing your needs for weight management with a trusted medical professional can clarify the best course of action.  

Prompt, Compassionate Health Care Services

If you’re seeking urgent care services in Alvin, La Marque, or Galveston, Texas, contact Affinity Urgent Care or schedule an appointment to receive prompt treatment. Our experienced team is here to provide efficient care when you need it most.