What Are GLP-1 Receptor Agonists, and How Do They Work?

GLP-1 receptor agonists have gained attention as breakthrough treatments for weight loss. But what exactly are GLP-1 receptor agonists, and how do they work? At Affinity Urgent Care, serving Alvin, La Marque, and Galveston, Texas, we empower our patients with knowledge regarding medical treatments so they can make informed decisions. If you’re exploring new options for weight management, this guide breaks down the essentials of GLP-1 receptor agonists.

How Does GLP-1 Work in the Body?

GLP-1, or glucagon-like peptide-1, is a hormone produced in the small intestine. It plays several key roles in the body, including:

• Stimulating insulin release to regulate blood sugar levels
• Sending signals to the brain to promote feelings of satiety
• Slowing down gastric emptying so your body releases less glucose into the bloodstream during digestion
• Blocking glucagon production (a hormone that increases blood sugar) to prevent glucose from entering the bloodstream

GLP-1 is crucial for regulating appetite. For those looking to lose weight, GLP-1 receptor agonists help by reducing hunger and increasing feelings of fullness, allowing for sustainable weight loss.

How Do GLP-1 Receptor Agonists Work?

Originally developed to treat type 2 diabetes, GLP-1 receptor agonists have been approved for weight management in people with obesity or weight-related health conditions. These medications, including semaglutide and tirzepatide, mimic the actions of the GLP-1 hormone in the body. They activate GLP-1 receptors in the pancreas and brain to help:

• Prevent blood sugar spikes after meals
• Curb appetite, as the brain receives stronger signals of fullness
• Keep blood sugar levels stable
• Improve insulin sensitivity

While highly effective, these medications are typically used alongside lifestyle changes like healthy eating and exercise for the best results.

Are GLP-1 Receptor Agonists Right for You?

GLP-1 receptor agonists can be an excellent option for individuals looking to manage their weight. However, patients must meet specific eligibility criteria and be aware of potential side effects and interactions. Schedule an appointment to find out if you are a good candidate.

Contraindications and Side Effects of GLP-1 Receptor Agonists

Certain medical conditions may make GLP-1 receptor agonists unsafe or impact their efficacy. Contraindications include the following:

• Pancreatitis
• Kidney disease
• Gastrointestinal disorders like gastroparesis
• History of medullary thyroid cancer
• Multiple endocrine neoplasia syndrome type 2 (MEN2)

GLP-1 therapies are not recommended during pregnancy, so individuals who are pregnant or planning to become pregnant should discuss alternatives with their medical team. Side effects may include nausea, digestive discomfort, or injection site reactions.

It’s important to talk to a medical professional about how GLP-1 therapy may fit into a comprehensive health care plan. During treatment, your provider will monitor your progress, adjust dosages, and provide nutritional guidance.

Supporting Your Health Every Step of the Way

If you want to learn more about GLP-1 receptor agonists for weight concerns, Affinity Urgent Care, serving Alvin, La Marque, and Galveston, Texas, is here to help. We offer personalized care and can help you explore your treatment options for weight management. Contact us to schedule an appointment.